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I I can tell you about my friend Andrew, the cognitive scientist. But it's not pretty. One evening he appeared with an infant in his arms at the door of his ex-wife, Martha. Because Briony, his lovely young wife after Martha, had died. Of what? We'll get to that. I can't do this alone, Andrew said, as Martha stared at him from the open doorway. It happened to have been snowing that night, and Martha was transfixed by the soft creature-like snowflakes alighting on Andrew's NY Yankees hat brim. Martha was like that, enrapt by the peripheral things as if setting them to music. Even in ordinary times, she was slow to respond, looking at you with her large dark rolling protuberant eyes. Then the smile would come, or the nod, or the shake of the head. Meanwhile the heat from her home drifted through the open door and fogged up Andrew's eyeglasses. He stood there behind his foggy lenses like a blind man in the snowfall and was without volition when at last she reached out, gently took the swaddled infant from him, stepped back, and closed the door in his face. This was where? Martha lived then in New Rochelle, a suburb of New York, in a neighborhood of large homes of different styles--Tudor, Dutch Colonial, Greek Revival--most of them built in the 1920s and '30s, houses set back from the street with tall old Norway maples the predominant trees. Andrew ran to his car and came back with a baby carrier, a valise, two plastic bags filled with baby needs. He banged on the door: Martha, Martha! She is six months old, she has a name, she has a birth certificate. I have it here, open the door please, Martha, I am not abandoning my daughter, I just need some help, I need help! The door opened and Martha's husband, a large man, stood there. Put those things down, Andrew, he said. Andrew did as he was told and Martha's large husband thrust the baby back into his arms. You've always been a fuck-up, Martha's large husband said. I'm sorry your young wife has died but I expect that she's dead of some stupid mistake on your part, some untimely negligence, one of your thought experiments, or famous intellectual distractions, but in any event something to remind us all of that gift you have of leaving disaster in your wake. Andrew put the baby in the baby carrier that lay on the ground, lifted the carrier with the baby, and walked slowly back to his car, nearly losing his balance on the slick path. He fastened a seat belt around the carrier in the backseat, returned to the house, picked up the plastic bags and the valise and carried them to the car. When everything was secured, he closed the car door, drew himself up, turned, and found Martha standing there with a shawl around her shoulders. All right, she said. [thinking] Go on. . . . No, I'm just thinking of something I read about the pathogenesis of schizophrenia and bipolar disease. The brain biologists are going to get to that with their gene sequencing, finding the variations in the genome--those protein suckers attached to the teleology. They'll give them numbers and letters, snipping away a letter here, adding a number there, and behold the disease will be no more. So, Doc, you're in trouble with your talking cure. Don't be too sure. Trust me, you'll be on unemployment. What else can we do as eaters of the fruit of the tree of knowledge but biologize ourselves? Expunge the pain, extend the life. You want another eye, say, in the back of your head? That can be arranged. Put your rectum in your knee? Not a problem. Even give you wings if you want, though the result would not be flying aloft but more like giant skips, floating megastrides as on those tracks that are like flattened escalators moving along the long airport corridors. And how do we know God would not want this, perfecting his fucked-up imperfect idea of life as an irremediable condition? We're his backup plan, his fail-safe. God works through Darwin. So Martha took the baby after all? I think also of how we decay in our rotting coffins, and how we reincarnate, the little microgenetic fragments of us sucked into the gut of a blind worm that rises it knows not why to wiggle in the rain-soaked soil only to die on the sharp beak of a house wren. Hey, that's my living genome-fragged ID shat from the sky and landing with a plop on the branch of a tree and dripping over the branch like a wet bandage. And lo! I am become a nutrient of a tree fighting for its life. That's true, you know, how those immobile standing-fast vascular creatures silently struggle for their existence as do we with one another, trees fighting for the same sun, the same soil in which they root themselves, and strewing the seeds that will become their forest enemies, like the princes to their king fathers in the ancient empires. But they're not completely motionless. In a high wind they do their dance of despair, the trees in heavy leaf swaying this way and that, throwing their arms up in their helpless fury of being what they are. . . . Well, it's a short step from anthropomorphism to hearing voices. You hear voices? Ah, I knew that would get your attention. Usually as I'm falling asleep. In fact I know I'm falling asleep when I hear them. And that wakes me up. I didn't want to tell you this and here I am telling you. What do they say? I don't know. Weird things. But I don't really hear them. I mean, they are definitely voices but at the same time they're soundless. Soundless voices. Yes. It's as if I hear the meanings of the words that are spoken without the sound. I hear the meanings but I know they are words that are spoken. Usually by different people. Who are these people? I don't know any of them. One girl asked me to sleep with her. Well, that's normal--a man would dream that. It's more than a dream. And I didn't know her. A girl in a long summer frock down to her ankles. And she wore running shoes. She had delicate freckles under her eyes, and her face seemed pale with sunlight even as she stood in the shade. Pretty enough to break your heart! She took my hand. Well, that's more than a voice, certainly more than a soundless voice. I think what happens is that I hear the meaning and provide an illustration in my mind. . . . So, might we get back to Andrew the cognitive scientist? I find myself reluctant to tell you that I hear the soundless voices too when I'm up and about in my daily life. But why shouldn't I? There was a morning on my way to work, for instance, when I had picked up my coffee and newspaper from the deli and was waiting at a stoplight. Watching the red seconds run down. And a voice said: As long as you're standing there, why don't you fix the screen door. It was so real, so close to an actual sounded voice, that I turned around to see who was in back of me. But there was no one, I was alone on that corner. And what was the illustration you provided when you heard that remark? It was an older woman. I put myself in her kitchen doorway. It was some sort of broken-down farm. I thought it might be in western Pennsylvania. There was an old flatbed truck in the yard. The woman wore a faded housedress. She looked up from the sink, totally unsurprised, and said that. At the kitchen table a small girl was drawing with a crayon. Was she the woman's granddaughter? I didn't know. She looked at me and turned back to her drawing and suddenly violently scribbled all over it with her crayon--whatever she had drawn she was now destroying. Are you in fact the man you call your friend Andrew, the cognitive scientist who brought an infant child to the home of his ex-wife? Yes. And are you telling me that you dreamt you ran away and found yourself standing at the screen door of some broken-down farmhouse somewhere? Well, it was not a dream, it was a voice. Try to pay attention. This voice brought back to me how it was when I needed to get away after my baby with Martha had died and my life with Martha with it. I didn't care where I went. I got on the first bus I saw at the Port Authority. I fell asleep on the bus, and when I woke it was winding its way through the hills of western Pennsylvania. We stopped at a small travel agency in one of these towns and I got off to walk around the town square: It was two or three in the morning, everything was closed of what there was, a drugstore, a five-and-ten, a picture framer, a movie theater, and taking up all one side of the square a sort of Romanesque courthouse. In the square of dead brown grass was a greenish-black Civil War statue of a man on a horse. By the time I got back to the travel agency, the bus was gone. So I walked out of town, over the railroad tracks, past some warehouses, and about a mile or two away--it was dawn now--I came upon this broken-down scrabbly-looking farm. I was hungry. I walked into the yard. No sign of life there so I walked around to the back of the house and found myself standing at a screen door. And there were these two just as I'd made them up or thought I had, the child and the old woman. And the old woman was the one who'd made that remark the morning I stood with my coffee and paper in Washington, D.C., waiting for the light to change. So what you're saying is that you ran away and found yourself at the actual screen door of some broken-down farmhouse somewhere in Pennsylvania that you'd previously imagined? No, dammit. That's not what I'm claiming. I did get on that bus and the trip was exactly as I've said. The shabby little town, the dirt farm. And when I got to the house it's true that those two people were in the kitchen, the old woman and the child with her crayons. There was also a roll of flypaper hanging under the ceiling light, and it was black with flies sticking to it. So it was all very real. But nobody asked me to fix the screen door. No? I'm the one who suggested that I fix it. I was tired and hungry. I didn't see a man anywhere. I thought if I offered some sort of handyman's help, they'd let me wash up, give me something to eat. I didn't want charity. So I smiled and said: Good morning. I'm a bit lost, but I see your screen door needs mending and I think I can fix it if you will offer me a cup of coffee. I'd noticed the door couldn't close properly, the upper hinge had pulled away from the frame, the mesh was slack. As a screen door it was quite useless, which is why they had hung flypaper from the ceiling light cord. So you see, it was not a preternatural vision that drew me to that place. I had taken that bus ride and seen that farm and those two people and then blanked them out of my mind until the morning in Washington when I was standing on the corner waiting for the red seconds to wind down and heard-- You were then working in Washington? --yes, as a government consultant, though I can't tell you doing what--and heard the voice of the old woman saying more or less what I had said when I appeared outside her screen door. Except in her voice the words had a judgmental tone--as if I had given her an insight into my hapless existence, to the effect of: "As long as you're standing there why don't you for once make yourself useful and fix the screen door." There's a term for this kind of experience in your manual, is there not? Yes. But I'm not sure we're talking about the same kind of experience. We have our manual too, you know. Your field is the mind, mine is the brain. Will the twain ever meet? What's important about that bus trip is that I had reached the point where I felt anything I did would bring harm to anyone I loved. Can you know what that's like, Mr. Analyst sitting in his ergonomic chair? I couldn't know in advance how to avoid disaster, as if no matter what I did something terrible would follow. So I got on that bus, just to get away, I didn't care. I wanted to tamp down my life, devote myself to mindless daily minutiae. Not that I had succeeded. What he said made that clear. What who said? Martha's large husband. When Andrew stepped inside the front door he saw Martha's large husband putting on his coat and hat and Martha walking up the stairs with the baby in her arms while turning back the little hood, unzipping the snowsuit. Andrew took note of a large well-appointed house, much grander than the house he and Martha had lived in as man and wife. The entrance hall had a dark parquet floor. Out of the corner of his eye he saw to his left a comfortable living room with stuffed furniture, and a fireplace with a fire going, and on the wall over the mantel the portrait of what he took to be some Russian czar in a long robe with an Orthodox cross on a chain and a crown that looked like an embroidered cap. To the right was a book-lined study with Martha's black Steinway. The staircase, carpeted in dark red with brass rods at the bottoms of the risers, was elegantly curved with a mahogany banister that Martha was not holding as she mounted the stairs with the baby in her arms. Martha wore slacks. Andrew noticed that she had maintained her figure and he found himself considering, as he hadn't for many years, the shape and tensile strength of her behind. The coat of Martha's large husband was of the round-shouldered style with a caped collar and sleeves that flared out. Nobody wore coats like that anymore. The hat, a sporty crushproof number, was too small for Martha's large husband's head. Excerpted from Andrew's Brain by E. L. Doctorow All rights reserved by the original copyright owners. Excerpts are provided for display purposes only and may not be reproduced, reprinted or distributed without the written permission of the publisher.