United by a desire to overcome their misfortunes, seven different women formed an indelible bond and vowed to right wrongs wherever they found them. After years known as the Vigilantes, Myra, Annie, Kathryn, Alexis, Yoko, Nikki, and Isabelle are enjoying their freedom and the chance at a normal life. But, President Martine Connor, their longtime ally, has announced the formation of a top-secret organization. For the Sisterhood, it's the end of an era, and the beginning of a new adventure.